NR+
(IM / IV)
NR+ (IM / IV)
Energize Your Cells & Elevate Your Life with NR!
This injection contains a coenzyme present throughout your body, designed to boost energy levels and enhance cognitive function, cellular health, and longevity.
Uses of NR are identical to that of NAD+. Improves cognitive function, energy, weight management, reduces pain, maintains muscle tone and function, supports metabolism, reduces and reverses aging, and more. It does this as a key function of our cells in the mitochondria that converts food to energy and maintains the integrity of our DNA. NAD aids in the production of ATP.
What is NR?
Niagen aka Nicotinamide Riboside (NR) is the precursor to NAD+ within the cell.
NR is also a product of extracellular NAD+ (eNAD).
By increasing NR, you are also indirectly feeding the NAD cycle as well but bypassing the need/process of and for the body to break down the NAD.
The benefits and functions of NR are identical to that of NAD, a coenzyme central to metabolism. NAD is found in all living cells and consists of two nucleotides joined through their phosphate groups. It acts as a coenzyme for redox reactions, making it central to energy metabolism.
What is NR used for?
Uses of NR are identical to that of NAD+.
It improves cognitive function, energy, weight management, reduces pain, reduces and reverses aging, and more.
It does this as a key function of our cells in the mitochondria that converts food to energy and maintains the integrity of our DNA.
NAD aids in the production of ATP.
It has a plethora of benefits, from improving athletic performance, reducing fatigue, high cholesterol, mood, blood pressure, slowly reducing aging, neurodegenerative diseases, and reversing alcohol effects on the liver.
Its mechanism of action as a coenzyme is part of the oxidoreductases in our body, which gives it the broad range of effects.
- Participation in over 400 enzyme reactions
- Production of fatty acids, cholesterol, bile acids, and steroid hormones
- Maintenance of muscle tone and function
- Supporting metabolism
NR+ Benefits
This infusion delivers an essential coenzyme directly into your bloodstream to boost energy levels and improve cognitive function, cellular health, and longevity, including decreasing the signs of aging.
- Boosts energy
- Repairs cells
- Reduces signs of aging
- Supports metabolism including fat metabolism & insulin resistance
- Boosts immunity
- Neuroprotective
- Supports cognitive function
- Supports mental clarity
- Helps with inflammation
- Fights oxidative stress
- May help with addiction recovery
What should I tell my care team before I take this medication?
• History of Cancer or significant family history of Cancer, genetic predisposition – as determined by Medical Director in consult
• Cardiovascular disease -History of severe heart failure, multiple medicated hypertensions, and arrhythmogenic issues – as determined by Medical Director in consult
• Pregnancy (there is no safety data for use of NR in pregnant clients); client must attest they are not pregnant to receive NR infusion(intravenous “IV”)/intramuscular injection (“IM”); if client is not absolutely positive she is not pregnant, then postponement and a client’s self-administered pregnancy test is recommended prior to beginning any course of NR IV/IM
• Breastfeeding (there is no safety data for use of NR in clients who are regularly engaged in breastfeeding a child); client must attest they are not breastfeeding to receive NR IV/IM
• Active Bleeding
• Thrombocytopenia
• Active Gastritis or peptic ulcer disease
• Impaired liver function
• Uncontrolled Diabetes
Should you experience any one or more of the below adverse reactions, side effects or complication during, immediately after or within 12 hours after completing an NR IV/IM. Please notify the service provider and be prepared to see a doctor IMMEDIATELY.
Some Potential Adverse Reactions, Side Effects or Complications to NR
- Headaches
- Malaise
- Chest Heaviness
- Tremors*
- Flushes*
- Fainting
- Nausea
- Irregular Sweating
- Tingling Sensation
- Malaise
- Sensations that can mimic feelings of a panic attack, etc.
- Insomnia
- Anxiety
- Difficulty Breathing*
- Shortness of Breath
- Dizziness
- Nausea
- Irregular Weakness
- Heart Rate Changes
- Skin Rash
*Denotes potential NAD toxicity (allergic hypersensitivity)
Some General IV Infusion Side Effects or Complications
- Infusion-Site Effects*
- Indigestion/Heartburn
- Vein Inflammation
- Dizziness
- Infection
- Headache
- Mild Diarrhea
- Lightheadedness
- Chills
- Fever
- Nausea/Upset Stomach
- Joint Pain
- Increased Thirst
- Severe Fatigue
- Shakes
*Infusion-site effects may include, without limitation, temporary pain, burning, bruising, blood, cellulitis or discoloration at the site of infusion.
Dried Blood Spot Testing for NAD+
NAD+ dried blood spot tests are available for patients receiving both Niagen (NR) and NAD+ treatments.
The primary environment of NAD+ activity is intracellular, as such; blood plasma levels are not indicative of bioavailability.
Intra RBC NAD+ can be measured through dried blood spot cards.
To use a dried blood spot card, fingers should be cleaned and disinfected.
A blood glucose lancet is used to perform a pin prick on the finger.
Blood is then transferred to a card and left to dry for 24 hrs in room air, then sealed and mailed to laboratory for processing.
Results are estimated to be available in 1-3 weeks.
NAD+ dried blood spots should be utilized before NAD+ or Niagen supplementation of any form to identify baseline. Sequential blood spots can then be utilized to guide supplemental regimen.